Corticospinal control of normal and visually-guided gait in healthy older and younger adults
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Corticospinal control of normal and visually-guided gait in healthy older and younger adults. / Spedden, Meaghan Elizabeth; Choi, Julia Tsok Lam; Nielsen, Jens Bo; Geertsen, Svend Sparre.
I: Neurobiology of Aging, Bind 78, 2019, s. 29-41.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Corticospinal control of normal and visually-guided gait in healthy older and younger adults
AU - Spedden, Meaghan Elizabeth
AU - Choi, Julia Tsok Lam
AU - Nielsen, Jens Bo
AU - Geertsen, Svend Sparre
N1 - CURIS 2019 NEXS 088
PY - 2019
Y1 - 2019
N2 - We investigated age-related differences in corticospinal control of muscle activity during normal and visually guided (VG) walking. Young (n = 15, 22.1 ± 1.7 years) and older (n = 15, 68.3 ± 2.7 years) participants performed normalwalking and VGwalking requiring precise foot placement based on visual cues. Coherence analysiswas used to quantify coupling between electroencephalography and electromyography from the anterior tibial muscle (corticomuscular) and between the 2 ends of the anterior tibial muscle (intramuscular) at 15-50 Hz during the swing phase of walking as markers of corticospinal activity. Our results indicated that corticomuscular and intramuscular coherencewas lower in older compared to young participants during both tasks. In addition, coherencewas generally greater during VG than during normal walking across age groups, although during late swing, older participants drove several of the observed task-related coherence increases. Performance on the VG task was lower in older compared to youngparticipants andwas correlated with task-related corticomuscular coherencemodulations within the older group. These results suggest age-related differences in the corticospinal control of walking, with possible implications for precision control of foot placement based on visual information.
AB - We investigated age-related differences in corticospinal control of muscle activity during normal and visually guided (VG) walking. Young (n = 15, 22.1 ± 1.7 years) and older (n = 15, 68.3 ± 2.7 years) participants performed normalwalking and VGwalking requiring precise foot placement based on visual cues. Coherence analysiswas used to quantify coupling between electroencephalography and electromyography from the anterior tibial muscle (corticomuscular) and between the 2 ends of the anterior tibial muscle (intramuscular) at 15-50 Hz during the swing phase of walking as markers of corticospinal activity. Our results indicated that corticomuscular and intramuscular coherencewas lower in older compared to young participants during both tasks. In addition, coherencewas generally greater during VG than during normal walking across age groups, although during late swing, older participants drove several of the observed task-related coherence increases. Performance on the VG task was lower in older compared to youngparticipants andwas correlated with task-related corticomuscular coherencemodulations within the older group. These results suggest age-related differences in the corticospinal control of walking, with possible implications for precision control of foot placement based on visual information.
KW - Faculty of Science
KW - Coherence
KW - Elderly
KW - Aging
KW - Walking
KW - Gait
KW - EEG
U2 - 10.1016/j.neurobiolaging.2019.02.005
DO - 10.1016/j.neurobiolaging.2019.02.005
M3 - Journal article
C2 - 30852367
VL - 78
SP - 29
EP - 41
JO - Neurobiology of Aging
JF - Neurobiology of Aging
SN - 0197-4580
ER -
ID: 214506101